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Diablo 4 Werewolf Druid Build – Toxic Shredder

Diablo 4 Werewolf Druid Build – Toxic Shredder – In this Diablo 4 Druid Class Build Guide I’ll show you how to play my Toxic Werewolf Build, which is a melee focused Diablo IV Werewolf Druid Build that uses Poison and Crowd Control to melt enemies overtime and from repeatedly swipes of claws. If you’ve been looking for a good Diablo 4 Werewolf Druid Build that focuses on the use of Werewolf then this Guide is for you!

Diablo 4 Werewolf Druid Build – Toxic Shredder

The general strategy for this Diablo 4 Werewolf Druid Build is to stack Poison DoT effects on enemies so that they melt quickly. This is accomplished via Skills like Vine Creeper, Rabies, Claw and Shred. All of these Poison DoTs can stack with one another, allowing you to wipe away nearly every enemy you see’s health while also maintaining a safe distance.

This Build also features quite a bit of Crowd Control, again in the form of Vine Creeper, but also through the use of the Legendary Aspect: Aspect of the Dark Howl, which turns Debilitating Roar from a Werebear Skill into a Werewolf one, and also allows it to Immobilize Poisoned enemies hit by it for nearly 4 seconds. This helps protect you and your group, and provides a means for these enemies to “bleed out” while they cannot move.

Diablo 4 Werewolf Druid Build –  Toxic Shredder Skill Distribution

Each Diablo 4 Werewolf Druid Build is made up of the 6 Active Skills they have equipped and changing these Skills can drastically change the way the Druid Class in Diablo IV plays. In this section we’ll take a look at what Skills you should slot for the Toxic Werewolf Diablo 4 Build. Your Skill distribution should look something like this:

Skill Points Spent
 Claw  1
 Enhanced Claw  1
 Fierce Claw  1
 Shred  5
 Enhanced Shred  1
 Raging Shred  1
 Predatory Instinct  3
 Blood Howl  1
 Enhanced Blood Howl  1
 Innate Blood Howl  1
 Debilitating Roar  1
 Enhanced Debilitating Roar  1
 Preserving Debilitating Roar  1
 Vine Creeper  2
 Enhanced Vine Creeper  1
 Ferocious Vine Creeper  1
 Rabies  1
 Enhanced Rabies  1
 Natural Rabies  1

The above list gives you the general order to invest in Skills, but keep in mind that you should prioritize picking up new Skills over investing in passives, so pick up passives later if you can get new Skills when you level up.

How to Handle Packs of Enemies

So there are really two ways that you’ll handle packs of enemies with this Diablo 4 Werewolf Druid Build, and that is by using Vine Creeper and Claw/Shred, OR by using Rabies and then Debilitating Roar and Claw/Shred. You can alternate between these methods so that your cooldowns don’t prevent you from moving quickly through Dungeons, but let’s get into these strategies.

Vine Creeper

Vine Creeper is one of the best all around Diablo 4 Druid Skills PERIOD! It should find a home in just about every Diablo 4 Druid Build because its Crowd Control is invaluable. But what this Skill does is it Immobilizes enemies in a rather large AoE radius and Poisons them all at the same time. This weakens enemies significantly while providing an opportunity to get in close and Shred enemies safely.

Make sure to upgrade Vine Creeper with Enhanced Vine Creeper and Ferocious Vine Creeper for a longer Immobilization duration and a longer Poison DoT effect. You want this thing to annihilate enemies, and it will!


Assuming you have the Spirit, you’ll then begin attacking this now Immobilized and Poisoned group of enemies with Shred trying to hit as many of them as you can. Make sure to complete the full 3 hit combo, because the last hit is deadly and also applies another Poison DoT of its own, allowing you to stack Poisons on enemies. This is your “go to ” Skill for this Build and you’ll use this just about every time you have the Spirit for it, since it melts enemies, Elites and Bosses alike. Always use it when you can, and make sure you take the Raging Shred upgrade!

Diablo 4 Werewolf Druid Build - Shred


If you don’t have the Spirit to use Shred then you’ll attack with Claw first until you do. Because we have the Enhanced Claw and Fierce Claw upgrades of this Skill it will also attack more quickly, as well as apply another Poison DoT of its own. This means between Vine Creeper, Shred and Claw you can now stack 3 Poison DoTs on one enemy at once. That damage really adds up, and it keeps ticking even when you are Dodging or moving around!


When Vine Creeper is on cooldown, or if you need added fire power for a fight with this Diablo 4 Werewolf Druid Build, you’ll use Rabies. Rabies applies a very high damaging Poison DoT to a target that spreads quickly, and even more quickly thanks to the Natural Rabies passive. This can quickly spread to all enemies in a group, wiping out a lot of HP at once. You don’t generally need both Vine Creeper and Rabies at once, but you should stack them for very tough trash pulls or when facing a Boss.

Diablo 4 Werewolf Druid Build - Rabies

Debilitating Roar

Debilitating Roar is a skill you wouldn’t generally use in this Diablo 4 Werewolf Druid Build, but because we have Aspect of the Dark Howl it fits very well allowing this Skill to Immobilize Poisoned enemies hit by it. We have tons of Poison so this works nicely for us. However, this Skill also reduces the damage enemies hit by it deal by 50%, Fortifies you, and also heals you as well, so it’s just generally good to have.

Diablo 4 Werewolf Druid Build - Debilitating Roar

If you don’t have the Aspect of the Dark Howl, you can use Ravens here in its place to get a source of Vulnerable and another AoE, but this is a really good one to have so I strongly recommend it.

Boss Fights

Boss fights are handled a bit differently than trash pulls because they cannot be Crowd Controlled, however, this Diablo 4 Werewolf Druid Build is still incredibly strong against Bosses.

When a Boss fight starts you’ll want to drop Vine Creeper and Rabies as quickly as you can to stack 2 Poison DoTs on the Boss, and then hit with Claw until you’ve build up some Spirit and then land a full Shred combo to stack a 4th Poison DoT. From this point onward you’ll keep alternating between Claw and Shred stacking Vine Creeper and Rabies whenever they come off cooldown, unless the Boss has minions, and then you’ll save these for those minions. Also use Debilitating Roar to debuff the boss and give you a bit extra healing whenever you can as well.

Blood Howl

You’ll use Blood Howl to heal whenever you need it, and this can save you a lot of Potions over the course of a Boss fight, and not too many Builds can actually heal themselves with a Skill the way you can with this one. Additionally, with the Innate Blood Howl passive it will provide you 20 Spirit, making it easier to use Shred more often. You will also use this in trash pulls, and kills reduce its cooldown which is excellent (if you have the Enhanced Blood Howl passive).

Diablo 4 Werewolf Druid Build - Blood Howl

Final Tips

Bonuses you want to look for on your gear are Critical Strike ChancePoison DamageDamage over TimeCore Skill DamageCrowd Control DurationDamage to Crowd Controlled EnemiesCooldown Reduction. The major focus here is on Critical Strikes and Crowd Control. Anything that you can take to increase these two things are valuable because you do both often, and Stormclaw’s Aspect will make you AoE with Shred when you Critically Strike, so make sure you get that when you can.

Vigorous Aspect is particularly good for this Build because it flat out reduces the damage you take while in Werewolf Form. Make sure you get this one as soon as you can!

Lastly, Exploiter’s Aspect is another good Legendary Aspect for this Build. It not only increases your Crowd Control Duration, but increases your damage against Unstoppable enemies (Bosses), which is really helpful. Be on the look out for this one!

Be sure to check out our Diablo 4 Wiki for any other questions you have about the game and the Builds page if you are looking for more Diablo IV Builds, as well as our Getting Started Guide and Best Class to Play in the Beta Guide if you are looking for more Diablo 4 content!

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